Anti-Annexin IV抗体This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品编号 yb-1564R
英文名称 Anti-Annexin IV抗体
中文名称 膜粘连蛋白 A4抗体
别    名 35 beta calcimedin; Carbohydrate binding protein P33/P41; DKFZp686H02120; Endonexin I; Lipocortin IV; P32.5; Annexin A4; Annexin IV placental anticoagulant protein II; ANX 4; ANX A4; ANX4; ANXA 4; LipocortinIV; P33/41; Placental anticoagulant protein II antibody PP4X; Proliferation inducing protein 28; ANXA4_HUMAN.
Anti-Annexin IV抗体
说 明 书 0.1ml  0.2ml  
研究领域 心血管  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Annexin IV
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.

Function:
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

Similarity:
Belongs to the annexin family. 
Contains 4 annexin repeats.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.