Anti-ABCG4抗体肾上腺髓质素（Adrenomedullin， AM）是广泛分布在肾上腺髓质、肺、心、肝、肾等器官。

产品编号 YB-1727R
英文名称 Anti-ABCG4抗体
中文名称 ABC膜转运蛋白抗体
别    名 ATP binding cassette, subfamily G member 4; ABCG 4; ATP binding cassette subfamily G member 4; WHITE 2; WHITE2; ABCG4_HUMAN.
Anti-ABCG4抗体  
说 明 书 0.1ml  0.2ml  
研究领域 免疫学  神经生物学  转运蛋白  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ABCG4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
he ATP binding cassette (ABC) superfamily of membrane transporters is one of the largest protein classes known, and counts for numerous proteins involved in trafficking of biological molecules across membranes. ABCG4 protein is highly expressed in both human and mouse brain, it is a 646aa molecule in human (chr 11q23) and mouse. It is an integral membrane protein may be involved in macrophage lipid homeostasis. The ABCG4 protein’s abundant expression in brain and close evolutionary relationship to the other members of the subfamily suggests a potential role in cholesterol transport.

Function:
May be involved in macrophage lipid homeostasis.

Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).

Similarity:
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
Contains 1 ABC transmembrane type-2 domain.
Contains 1 ABC transporter domain.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.