Anti-ALF抗体脂肪炎症因子apelin是血管紧张素Ⅱ-1型受体相关蛋白的天然内源性配体，是新发现的小分子活性多肽，为孤儿G蛋白偶联受体一血管紧张素受体AT-1相关蛋白（APJ）的天然配体具有调节心血管系统稳态、扩张血管、降低血压、调节免疫等多种生物学作用。

产品编号 yb-5139R
英文名称 Anti-ALF抗体
中文名称 通用转录因子IIA样因子抗体
别    名 General transcription factor II A 1 like factor; GTF2A1LF; SALF; Stonin 1; TFIIA alpha and beta like factor; TF2AY_HUMAN; 1-like factor; General transcription factor II A; Gtf2a1l; TFIIA-alpha and beta-like factor.
Anti-ALF抗体
说 明 书 0.1ml  0.2ml  
研究领域 免疫学  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALF
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involves the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. ALF is a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.

Function:
May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis specific.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

通用转录因子IIA样因子抗体又称TFIIAα/β样因子抗体。