Anti-Annexin A7抗体也称βA4 蛋白，是β-淀粉样蛋白前体（APP）经β和γ分泌酶分解后的产物，有39-43个氨基酸残基组成。是淀粉样蛋白的主要成分。

产品编号 yb-5917R
英文名称 Anti-Annexin A7抗体
中文名称 膜粘连蛋白7抗体
别    名 Annexin VII; AnnexinVII; Annexin A7; ANX7; ANXA7; SNX; Synexin; Annexin-7; ANXA7_HUMAN.
 Anti-Annexin A7抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Annexin A7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
产品介绍 background:
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximay 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.

Subunit:
Interacts with PDCD6.

Tissue Specificity:
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.

Similarity:
Belongs to the annexin family. 
Contains 4 annexin repeats.

 
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.