Anti-Annexin A9抗体ANXA9 may act as a low affinity receptor for acetylcholine and is expressed in the stratified squamous skin epithelium,

产品编号 yb-5916R
英文名称Anti-Annexin A9抗体
中文名称 膜粘连蛋白9抗体
别    名 annexin 31; annexin A9; annexin XXXI; ANX31; ANXA9; ANXA 9; ANXA-9; pemphaxin; ANXA9_HUMAN .
nti-Annexin A9抗体 
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Annexin A9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
nti-Annexin A9抗体
PubMed PubMed
产品介绍 background:
ANXA9 may act as a low affinity receptor for acetylcholine and is expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). ANXA9 is one of the target molecules recognized by autoantibodies in patients with pemphigus vulgaris, a rare, autoimmune skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.

Function:
Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.

Subunit:
Homodimer.

Tissue Specificity:
Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).

Similarity:
Belongs to the annexin family. 
Contains 4 annexin repeats.

Database links:
UniProtKB/Swiss-Prot: O76027.3
nti-Annexin A9抗体
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.