Anti-Alpha 1 acid glycoprotein 2抗体This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant.

产品编号 yb-7565R
英文名称 Anti-Alpha 1 acid glycoprotein 2抗体
中文名称 α1酸性糖蛋白2/类粘蛋白2抗体
别    名 AGP 2; AGP B; AGP2; Alpha 1 acid glycoprotein 2; Alpha 1 acid glycoprotein type 2; OMD 2; ORM 2; Orosomucoid2; A1AG2_HUMAN.
Anti-Alpha 1 acid glycoprotein 2抗体   
说 明 书 0.1ml  0.2ml  
研究领域 心血管  细胞生物  免疫学  糖蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Alpha 1 acid glycoprotein 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008].

Function:
Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma. 

Post-translational modifications:
N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor). 

Similarity:
Belongs to the calycin superfamily. Lipocalin family.

Database links:
UniProtKB/Swiss-Prot: P19652.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.