Anti-ACSM3抗体ACSM3 is a 586 amino acid protein has a broad substrate specificity and utilizes magnesium as a cofactor.

产品编号 yb-7641R
英文名称 Anti-ACSM3抗体
中文名称 丁酰基*合成酶3抗体
别    名 Butyryl coenzyme A synthetase 3; mitochondrial; ACSM3; ACSM3_HUMAN; Acyl CoA synthetase medium chain family member 3; Acyl-CoA synthetase medium-chain family member 3; Acyl-coenzyme A synthetase ACSM3; Acyl-coenzyme A synthetase ACSM3, mitochondrial; Butyrate CoA ligase 3; Butyrate--CoA ligase 3; Butyryl-coenzyme A synthetase 3; Middle chain acyl CoA synthetase 3; Middle-chain acyl-CoA synthetase 3; Protein SA homolog; SA (rat hypertension associated) homolog; SA antibody SA hypertension associated homolog; SA, rat, homolog of; SAH.
Anti-ACSM3抗体 
说 明 书 0.2ml  
研究领域 心血管  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACSM3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
ACSM3 is a 586 amino acid protein has a broad substrate specificity and utilizes magnesium as a cofactor. The gene encoding ACSM3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Function:
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro)

Subcellular Location:
Mitochondrion matrix 

Similarity:
Belongs to the ATP-dependent AMP-binding enzyme family. 

Database links:

Entrez Gene: 6296 Human

Entrez Gene: 20216 Mouse

Omim: 145505 Human

SwissProt: Q53FZ2 Human

SwissProt: Q3UNX5 Mouse

Unigene: 706754 Human

Unigene: 334199 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.