Anti-APOL3抗体E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5.

产品编号 yb-7967R
英文名称 Anti-APOL3抗体
中文名称 载脂蛋白L3抗体
别    名 ApoL III; APOLIII; Apolipoprotein L 3; Apolipoprotein L III; Apolipoprotein L3; Apolipoprotein LIII; CG12 1; TNF inducible protein CG12 1; APOL3_HUMAN.
Anti-APOL3抗体   
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human APOL3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
APOL3 may be involved in cytoplasmic lipid transport or allow the binding of lipids to organelles. It is widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and testis. There are three named isoforms.

Function:
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. 

Subcellular Location:
Cytoplasm (Probable). 

Tissue Specificity:
Widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and testis.

Similarity:
Belongs to the apolipoprotein L family. 

Database links:
UniProtKB/Swiss-Prot: O95236.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.