Anti-ABCF2抗体ATP-binding cassette （ABC） transporters are an evolutionarily conserved family of widely-expressed proteins that

产品编号 yb-12441R
英文名称 Anti-ABCF2抗体
中文名称 ATP结合盒转运蛋白2抗体
别    名 0710005O05Rik; ABC28; ABCF 2; ATP binding cassette sub family F (GCN20) member 2; DKFZp586K1823; Drr3; E430001O06; EST133090; fb04f06; fc74f03; fd58d07; HUSSY 18; MABC1; MGC128735; ABCF2_HUMAN.
Anti-ABCF2抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  信号转导  转录调节因子  转运蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ABCF2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC genes comprise several subfamilies. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell, as part of a metabolic process, or outside the cell, for transport to other organs or for secretion from the body. ABCF2 in particular plays a putative role in tumor suppression at metastatic sites and in the endocrine pathway for breast cancer and may be a prognostic marker for clear cell ovarian adenocarcinoma.

Function:
ABCF 2 is a member of the ABC Transporter superfamily and of the GCN20 subfamily. As a member of the ABC Transporter family, it functions to transport various molecules across extra- and intracellular membranes.

Similarity:
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Contains 2 ABC transporter domains. 

Database links:
UniProtKB/Swiss-Prot: Q9UG63.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.