Anti-Arginase 1抗体APMAP is a 416 amino acid single-pass type II membrane protein that belongs to the strictosidine synthase family and is thought to play

产品编号 yb-12490R
英文名称 Anti-Arginase 1抗体
中文名称 脂肪细胞膜相关蛋白抗体
别    名 Adipocyte plasma membrane associated protein; Adipocyte plasma membrane-associated protein; apmap; APMAP_HUMAN; BSCv; BSCv protein; C20orf3; Chromosome 20 open reading frame 3; Protein BSCv.
 Anti-Arginase 1抗体   
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Monkey, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human APMAP
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 Anti-Arginase 1抗体
PubMed PubMed
产品介绍 background:
APMAP is a 416 amino acid single-pass type II membrane protein that belongs to the strictosidine synthase family and is thought to play a role in adipocyte differentiation. The gene encoding C20orf3 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception. 

Function:
Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.

Subcellular Location:
Membrane.

Tissue Specificity:
Liver, glomerular and tubular structures of the kidney, endothelial cells, arterial wall and pancreatic islets of Langerhans (at protein level). Found ubiquitously in adult as well as in embryonic tissues. In adult tissue, the highest expression is found in the liver, placenta and heart. Found on the cell surface of monocytes. In embryonic tissue, the highest expression levels is found in the liver and the kidney.

Similarity:
Belongs to the strictosidine synthase family.
 Anti-Arginase 1抗体
Database links:
UniProtKB/Swiss-Prot: Q9HDC9.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.