Anti-Connexin-37S抗体The Connexin 37/GJA4 gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of

产品编号 yb-4067R
英文名称 Anti-Connexin-37S抗体
中文名称 间隙连接蛋白37抗体
别    名 Connexin37; Connexin-37; Connexin 37; CX37; Gap junction alpha 4 protein; gap junction protein, alpha 4 37kDa (connexin 37); gap junction protein, alpha 4, 37kD (connexin 37); GJA4; CXA4_HUMAN; Gap junction alpha-4 protein; OTTHUMP00000004181; OTTHUMP00000004182.
Anti-Connexin-37S抗体    
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  免疫学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Guinea Pig, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Connexin 37
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The Connexin 37/GJA4 gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.