Anti-CKS1抗体CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

产品编号 yb-5745R
英文名称 Anti-CKS1抗体
中文名称 细胞周期蛋白依赖性激酶调节亚基1抗体
别    名 CDC2 associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1B; Cell division control protein CKS1; CKS 1; CKS1B; Ckshs1; Cyclin dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS 143; PNAS 16; PNAS 18.
Anti-CKS1抗体   
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  免疫学  细胞周期蛋白  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9.6kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CKS1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.

Function:
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

Subunit:
Forms a homohexamer that can probably bind six kinase subunits.

Similarity:
Belongs to the CKS family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.