Anti-Cystatin E抗体Shows moderate inhibition of cathepsin B but is not active against cathepsin C.

产品编号 yb-6042R
英文名称 Anti-Cystatin E抗体
中文名称 半*蛋白酶抑制剂6抗体
别    名 CST 6; CST-6; CST6; Cystatin 6; Cystatin E; Cystatin E/M; Cystatin M; Cystatin M/E; Cystatin-6; Cystatin-E; Cystatin-M; Cystatin6; CystatinE; CystatinM; Cysteine proteinase inhibitor; CYTM_HUMAN.
Anti-Cystatin E抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13.6kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cystatin E/M
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Shows moderate inhibition of cathepsin B but is not active against cathepsin C.

Function:
Shows moderate inhibition of cathepsin B but is not active against cathepsin C.

Subcellular Location:
Secreted.

Tissue Specificity:
Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.

Post-translational modifications:
Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor.

Similarity:
Belongs to the cystatin family.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.