Anti-CMG1抗体细胞色素P450 2E1（CYP2E1）可被乙醇等化合物诱导, 参与多种前致癌物（N-亚硝胺、苯胺、氯乙烯、氨基甲酸乙酯）的代谢活化,诱发肿瘤的发生。

产品编号 yb-7050R
英文名称 Anti-CMG1抗体
中文名称 毛细管形态发生蛋白1抗体
别    名 Capillary morphogenesis gene 1 protein; Capillary morphogenesis protein 1; Ccdc2; CMG 1; CMG-1; Coiled-coil domain containing 2; Coiled-coil domain-containing protein 2; IFT74; IFT74_HUMAN; intraflagellar transport 74 homolog; Intraflagellar transport protein 74 homolog.
Anti-CMG1抗体  
说 明 书 0.2ml  
研究领域 心血管  细胞外基质  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 69kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CMG1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
No data available.

Subcellular Location:
Cytoplasmic vesicle. Note=Intracellular vesicular compartment.

Tissue Specificity:
Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.