Anti-CCortexin 1抗体Cortexin 1 and Cortexin 3 are single-pass membrane proteins. Cortexin 1 may be involved in mediating extracellular or intracellular signaling of cortical neurons

产品编号 yb-11829R
英文名称 Anti-CCortexin 1抗体
中文名称 皮质素1抗体
别    名 Cortexin-1; Cortexin1; Ctxn1; CTXN1_HUMAN; FLJ25968.
Anti-CCortexin 1抗体   
说 明 书 0.2ml  
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, 
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cortexin 1 (31-82aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Cortexin 1 and Cortexin 3 are single-pass membrane proteins. Cortexin 1 may be involved in mediating extracellular or intracellular signaling of cortical neurons during forebrain development. Cortexin 3 is specifically expressed in kidney and brain. Exsiting as two isoforms due alternative splicing, cortexin 3 may mediate extracellular or intracellular signaling in the kidney or brain.

Function:
May mediate extracellular or intracellular signaling of cortical neurons during forebrain development.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Similarity:
Belongs to the cortexin family.

Database links:
UniProtKB/Swiss-Prot: P60606.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.