Anti-C9orf98抗体Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination,

产品编号 yb-15351R
英文名称 Anti-C9orf98抗体
中文名称 9号染色体开放阅读框98抗体
别    名 adenylate kinase 8; chromosome 9 open reading frame 98; DDX31; Putative adenylate kinase like protein C9orf98; putative adenylate kinase-like protein C9orf98; KAD8_HUMAN.
Anti-C9orf98抗体  
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C9orf98
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic angiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf98 gene maps to human chromosome 9q34.13. Consisting of 479 amino acids, C9orf98 exists as two alternatively spliced isoforms and belongs to the adenylate kinase family.

Function:
Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.

Subcellular Location:
Cytoplasm, cytosol.

Similarity:
Belongs to the adenylate kinase family.

Database links:

Entrez Gene: 158067 Human

SwissProt: Q96MA6 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.