Anti-CDC42EP3抗体CDC42EP3 is probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly

产品编号 yb-13759R
英文名称 Anti-CDC42EP3抗体
中文名称 CDC42效应蛋白3抗体
别    名 Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; Cdc42 effector protein 3; CEP3; CRIB containing BORG2 protein; MSE55 related Cdc42 binding protein; MSE55 related protein; UB1.
Anti-CDC42EP3抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  神经生物学  细胞骨架  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDC42EP3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
CDC42EP3 is probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. It induces pseudopodia formation in fibroblasts. 

Subcellular Location:
Endomembrane system; Peripheral membrane protein. Cytoplasm; cytoskeleton.

Similarity:
Belongs to the BORG/CEP family.