Anti-COQ3抗体Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes

产品编号 yb-13985R
英文名称 Anti-COQ3抗体
中文名称 线粒体COQ3抗体
别    名 3 4 dihydroxy 5 hexaprenylbenzoate methyltransferase; bA9819.1; Coenzyme Q3 homolog methyltransferase (S. cerevisiae); Coenzyme Q3 homolog methyltransferase (yeast); Coenzyme Q3 homolog methyltransferase; COQ 3; DHHB methyltransferase; DHHB MT; DHHB MTase; DHHBMT; DHHBMTASE; Dihydroxyhexaprenylbenzoate methyltransferase; Hexaprenyldihydroxybenzoate methyltransferase; Hexaprenyldihydroxybenzoate methyltransferase mitochondrial; Methyltransferase COQ3; OTTHUMP00000016892; UG0215E05.
Anti-COQ3抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  信号转导  细胞类型标志物  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COQ3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

Function:
COQ3 (Coenzyme Q3 homolog, methyltransferase) is an O-methyltransferase essential in the biosynthetic pathway of coenzyme Q (ubiquinone).

Subcellular Location:
Mitochondrion matrix.
 
Similarity:
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.