Anti-CPEB2抗体The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein （CPEB）, an mRNA-binding protein that regulates

产品编号 yb-14019R
英文名称 Anti-CPEB2抗体
中文名称 细胞质多聚腺苷酸结合蛋白2抗体
别    名 CPE binding protein 2; CPE BP2; CPEB 2; CPEBP2; Cytoplasmic polyadenylation element binding protein 2; hCPEB 2; hCPEB2; CPEB2_HUMAN.
 Anti-CPEB2抗体
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  信号转导  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CPEB2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
v
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
CPEB2, (Cytoplasmic polyadenylation element-binding protein 2), belongs to the RRM CPEB family and contains 2 RRM (RNA recognition motif) domains. It may bind poly(U) RNA oligomers. It may play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. There are 7 named isoforms [FASTA] produced by alternative splicing. 

Subcellular Location:
Cytoplasmic
 
Similarity:
Belongs to the RRM CPEB family.
Contains 2 RRM (RNA recognition motif) domains.