Anti-CRISP1抗体Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes.

产品编号 yb-14058R
英文名称 Anti-CRISP1抗体
中文名称 富含半*分泌蛋白1抗体
别    名 Acidic epididymal glycoprotein homolog; Acidic epididymal glycoprotein like 1; AEG like protein; AEG related protein; AEG-like protein; AEGL1; ARP; CRIS1_HUMAN; CRISP-1; CRISP1; Cysteine rich secretory protein 1; Cysteine rich secretory protein 1 delta; Cysteine-rich secretory protein 1; HSCRISP1D; HSCRISP1G; HUMARP; Protein DE like.
 Anti-CRISP1抗体    
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  发育生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CRISP1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
产品介绍 background:
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Function:
May have a role in sperm-egg fusion and maturation.

Subcellular Location:
Note=Located in the lumen and epithelium of distal ductus efferentes and epididymal ducts, and on the postacrosomal region of the sperm head.

Tissue Specificity:
Caput, corpus, and cauda regions of the epididymis, the ductus deferens, sperm and seminal plasma.
 
Similarity:
Belongs to the CRISP family. 
Contains 1 SCP domain.
Contains 1 ShKT domain.