Anti-CYLC1抗体The cytoskeletal calyx structure surrounds part of the nucleus of the mammalian sperm head and contains two main types

产品编号 yb-14143R
英文名称 Anti-CYLC1抗体
中文名称 CYLC1蛋白抗体
别    名 Cylicin 1; CYCL1; CYLC1; CYLC1_HUMAN; Cylicin I; Cylicin, basic protein of sperm head cytoskeleton 1; Cylicin-1; Multiple band polypeptide I; Multiple-band polypeptide I; OTTHUMP00000023617.
 Anti-CYLC1抗体  
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  发育生物学  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CYLC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 
PubMed PubMed
产品介绍 background:
The cytoskeletal calyx structure surrounds part of the nucleus of the mammalian sperm head and contains two main types of basic proteins: calicin and the multiple band proteins (MBPs). Cylicin-1, a member of the MBP family, contains several lysine dipeptides followed by a third variable amino acid, which, in most cases, is aspartic acid. The central portion of the protein is arranged as a series of repeating units that are predicted to form short individual a-helices which are interrupted by short linker segments. The C-terminal tail of Cylicin-1 contains proline-rich segments. Cylicin-1 is ex-pressed only in the calyx of human and cow spermatozoa, and has a possible architectural role during spermiogenesis.

Function:
Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.

Subcellular Location:
Cytoplasm > cytoskeleton > perinuclear theca > calyx. Sperm head cytoskeletal structure.