Anti-ASAP3抗体ASAP3 is a member of a subfamily of ADP-ribosylation factor（Arf） GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains.

产品编号 yb-5832R
英文名称 Anti-ASAP3抗体
中文名称 GTP酶激活蛋白ASAP3抗体
别    名 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1; ACAP4; Arf GAP with SH3 domain; Arf GAP with SH3 domain, ANK repeat and PH domain containing protein 3; ARF6 GTPase activating protein; ArfGAP with SH3 domain, ankyrin repeat and PH domain; Centaurin, beta 6; CENTB6; DDEFL1; Development and differentiation enhancing factor like 1; Up regulated in liver cancer 1 (UPLC1); UPLC1.
Anti-ASAP3抗体 
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  免疫学  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ASAP3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
ASAP3 is a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion.

Function:
Promotes cell proliferation.

Subunit:
Cytoplasm.

Tissue Specificity:
Highly expressed in primary hepatocarcinoma. Detected in lung, liver and blood leukocytes.

Similarity:
Contains 2 ANK repeats.
Contains 1 Arf-GAP domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 55616 Human

Entrez Gene: 523797 Cow

SwissProt: Q8TDY4 Human

Unigene: 437379 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.