Anti-ADAM11抗体β1肾上腺素能受体（Beta-adrenergic Receptor-1 ）在接受交感神经节后纤维支配的各种器官中存在着与肾上腺素、*起反应的受体，称为肾上腺素能受体。

产品编号 yb-5846R
英文名称 Anti-ADAM11抗体
中文名称 去整合素样金属蛋白酶11抗体
别    名 A disintegrin and metalloproteinase domain 11; ADA11_HUMAN; MDC; Metalloproteinase like, disintegrin like, and cysteine rich protein.
Anti-ADAM11抗体   
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  信号转导  细胞骨架  细胞外基质  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADAM11
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008]. 

Function:
Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.

Subunit:
Can bind to LGI1 and LGI4.

Subcellular Location:
Membrane; Single-pass type I membrane protein. 

Tissue Specificity:
Expressed predominantly in brain. Slightly detected or not at all in other tissues. 

Post-translational modifications:
The precursor is cleaved by a furin endopeptidase.

Similarity:
Contains 1 disintegrin domain. 
Contains 1 EGF-like domain. 
Contains 1 peptidase M12B domain.


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.