Anti-CD200抗体是Ⅰ型膜糖蛋白，为免疫球蛋白超家族的新成员，广泛表达在人类胸腺细胞、B细胞、激活的T细胞、滤泡状树突细胞、神经元及血管内皮上。

产品编号 1680-6030R
英文名称 Anti-CD200抗体
中文名称 膜糖蛋白CD200抗体
别    名 CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G_HUMAN.
Anti-CD200抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  免疫学  细胞表面分子  糖蛋白  淋巴细胞  t-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD200
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 Function:
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

Subunit:
Interacts with CD200R1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID:
4345

Database links:

Entrez Gene: 4345 Human

Omim: 155970 Human

SwissProt: P41217 Human

Unigene: 79015 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

是Ⅰ型膜糖蛋白，为免疫球蛋白超家族的新成员，广泛表达在人类胸腺细胞、B细胞、激活的T细胞、滤泡状树突细胞、神经元及血管内皮上。可表达于B细胞及其增殖性疾病和一部分T细胞。近年来研究发现，CD200与CD200R间的相互作用可以传递抑制性信号减低髓样细胞的活性，改变其迁移。CD200在免疫疾病和抑制排斥反应中作为一种免疫耐受信号，它的一些相关分子在免疫调节中也具有一定的作用。