Anti-CST7抗体The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences.

产品编号 yb-6039R
英文名称 Anti-CST7抗体
中文名称 半*蛋白酶抑制剂7抗体
别    名 CMAP; CST 7; CST7; Cystatin 7; Cystatin-7; Cystatin7; Cystatin like metastasis associated protein; CystatinF; Cystatin-F; Cystatin F; Leukocystatin.
Anti-CST7抗体
说 明 书 0.1ml  0.2ml  
研究领域 心血管  细胞生物  免疫学  信号转导  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
细胞定位 细胞浆 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cystatin F
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.

Function:
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted. Cytoplasm.

Tissue Specificity:
Primarily expressed in peripheral blood cells and spleen.

Similarity:
Belongs to the cystatin family.

Database links:
UniProtKB/Swiss-Prot: O76096.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.