Anti-Dynamin 3抗体Dynamin III is a microtubule-associated, force-producing GTPase that can form helical structures around the neck of vesicles.

产品编号 bsyb343R
英文名称 Anti-Dynamin 3抗体
中文名称 酶动力蛋白3抗体
别    名 Dynamin III; testicular; DNM 3; DNM3; DNM3 protein; Dyn3; DYN3_HUMAN; Dyna III; DynaIII; dynamin 2; Dynamin; Dynamin family member; Dynamin testicular; Dynamin-3; Dynamin3; EC 3.6.5.5; KIAA0820; MGC70433; T dynamin; T-dynamin.
Anti-Dynamin 3抗体 
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  神经生物学  信号转导  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Dynamin 3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Dynamin III is a microtubule-associated, force-producing GTPase that can form helical structures around the neck of vesicles. GTP hydrolysis-dependent extension of the helical structure releases the vesicle. Dynamin III contains a pair of phosphorylation sites at Ser 759 and Ser 763. Both 3.0 and 7.2 kb Dynamin III transcripts are detectable in brain. The 3.0 kb Dynamin III transcript is also detectable in testis. The 7.2 kb Dynamin III transcript is brain-specific for a protein thought to influence synaptogenesis in the CNS through recycling, neurotransmitter reuptake and growth factor-receptor signaling, in a thyroid hormone-dependent manner. A 6 kb antisense transcript (Dnm3os) contained within an intron of the mouse Dnm3 gene may be under transregulation by twist during mouse development. Dynamin III and Dnm3os transcripts overlap during embryogenesis and in adult tissues, except that Dynamin III is abundant in adult brain and testis whereas Dnm3os is abundant in embryos and gravid uterus.
Function:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis